Although specific IgE to peanut in infants (15.18%), children (8.26%), or adults (7.14%) were more common than for sesame seed (3.79, 2.65, and 1.91%, respectively), among the 93 patients reviewed clinically, peanut-induced allergic reactions were mild, in contrary to sesame seed where anaphylaxis was the only clinical manifestation. The gene discussed is IGHE; the disease is anaphylaxis.