It has also been demonstrated that TGF-β can increase the release of vascular endothelial growth factor (VEGF) in addition to having a significant anti-inflammatory effect.7 Another important cytokine is TNF-α, which has a role in the host immune response to infection, angiogenesis induction, tissue repair and regeneration, regulation of proliferation and tissue differentiation.7,8. The gene discussed is VEGFA; the disease is infection.