Also, in another study on muscle biopsy from a patient with centronuclear myopathy, caused by a mutation within the dynamin 2 gene, we detected MVI on the surface of the calthrin-, muscle synapse component, and dystrophin-containing vacuoles accumulated within the fibers, which further confirms a role of MVI in vesicular trafficking within muscle fibers (Karolczak et al. 2011). The gene discussed is DNM2; the disease is autosomal dominant centronuclear myopathy.