For a pathway-based stratification of CRC tumor samples, we selected four pathways known to play a role in progression of CRC: MAPK signaling (KEGG: hsa04010), mTOR signaling (KEGG: hsa04150), ErbB signaling (KEGG: hsa04012), and colorectal cancer disease pathway (CRCdp, KEGG: hsa05210). The gene discussed is EGFR; the disease is colorectal cancer.