The results showed that there was an increased fraction of Annexin V+/7-AAD− (early apoptosis) and Annexin V+/7-AAD+ (late apoptosis) in Ad-IFNγ-infected NPC cells than those of Ad-LacZ-infected cells (CNE-2, 21.2% vs 5.3%, p<0.01; C666-1, 16.3% vs 6.4%, p<0.01) (Figure 3A). The gene discussed is ANXA5; the disease is nasopharyngeal carcinoma.