Here we found that both G1 phase arrest and apoptosis contributed to Ad-IFNγ-mediated growth suppression in NPC cell lines (Figure 2B, Figure 3 and Figure 6), consistent with the report that the antiproliferative effects of minicircle-IFNγ on NPC cell lines could be attributed to G1 arrest and apoptosis [9]. This evidence concerns the gene IFNG and nasopharyngeal carcinoma.