We have previously used the same cellular model [30] and have found that DUX4 is expressed in a higher number of myonuclei in FSHD myotubes than in control myotubes and that the level of DUX4 expression is higher in the myonuclei of atrophic myotubes. The gene discussed is DUX4; the disease is facioscapulohumeral muscular dystrophy.