Candidate SNPs selected from ABCB1, ABCG2, CYP3A5 and PXR genes were present with high variant allele frequency ranging from 20% to 70% in the patients with CML which was also comparable with healthy subjects from the 3 ethnic groups (Table S1). This evidence concerns the gene ABCB1 and chronic myelogenous leukemia, BCR-ABL1 positive.