AFP and hepatocellular carcinoma: The 8 subgroups of HCC patients were identified as ‘tumor multiplicity (multiple)’, ‘tumor size (≥5 cm)’, ‘HBsAg (positive)’, ‘serum AFP (≥20 ng/ml)’, ‘grade (III–IV)’, ‘cirrhosis (yes)’, ‘stage (III–IV)’, and ‘relapse (yes)’.