Several studies have demonstrated that IL-2 release stimulated by TB-specific antigens were significantly higher in TB patients than healthy controls and suggested that IL-2 could be a potential biomarker for diagnosing TB infection [17], [18], [19], and for discriminating ATB and LTBI when tested with a long incubation time (72 h) [20], though other study indicated that IL-2 might not be useful as a stand-alone diagnostic biomarker for TB infection due to its low amount in release [21]. The gene discussed is IL2; the disease is tuberculosis.