Interestingly, in the study by Lin et al, a transient androgen treatment was unable to induce TMPRSS2: ERG fusion in non-malignant prostate epithelial cells even in the presence of genotoxic stress, indicating the presence of repair mechanism in non-malignant prostate epithelial that suppress genetic instability, which has been abrogated in prostate cancer cells [5]. The gene discussed is ERG; the disease is prostate carcinoma.