TNFSF13B and lymphoma: After interaction with BAFF-R and other receptors, BAFF activates NF-κB, which leads to the resistance to apoptosis of lymphoma B cells by upregulation of the antiapoptotic proteins Bcl-2, Bcl-xL, and Mcl-1 and downregulation of proapoptotic proteins such as Bax [9], [28], [29], [30], [31].