HIF1A and cancer: The data from several experimental studies have indicated that hypoxia-induced higher expression of miR-210 is associated with hypoxia-induced downstream targets VEGF and carbonic anhydrase 9 (CAIX) in cancer cells by a HIF-1α-dependent mechanism [15], [32], which suggests that miR-210 may have a regulatory role in the promotion of tumor angiogenesis [11]–[13], [23], [33], [34].