For pTa tumours, the most common of the four possible groups (wild-type FGFR3 plus wild-type TP53, wild-type FGFR3 plus mutated TP53, mutated FGFR3 plus wild-type TP53, mutated FGFR3 plus mutated TP53) was tumours with mutated FGFR3 and wild-type TP53 (208/336; 61.9% of cases), followed by tumours wild-type for both FGFR3 and TP53 (106/336; 31.5% of cases). The gene discussed is FGFR3; the disease is neoplasm.