In contrast to higher serum creatinine being a strong predictor of 30-day and 1-year mortality following TAVI [9], we did not find any similar association with cystatin C. Probably the post-operative values of cystatin C and its dynamics during the peri-operative course should be studied for early diagnostics of AKI or adverse prognosis after TAVI. The gene discussed is CST3; the disease is acute kidney injury.