ACE and metabolic syndrome: Subgroup analysis showed that beneficial effects of PIA on VAs tended to be observed in most subgroups (i.e. ≥65 (OR 0.47; 95% CI: 0.20–1.06; p = 0.068) and <65 y (OR 0.29; 95% CI: 0.08–1.03; p = 0.056), female (OR 0.24; 95% CI: 0.05–1.07; p = 0.062) and male (OR 0.47; 95% CI: 0.21–1.03; p = 0.060), with dyslipidemia (OR 0.35; 95% CI: 0.11–1.10; p = 0.072) and without (OR 0.43; 95% CI: 0.18–1.03, p = 0.059) and with or without acute treatment such as PCI, ACE inhibitors or statins.