CD4 and Opportunistic infection: Abbreviations: CD4 = cell differential count; HIV-1 RNA = human immunodeficiency virus-1 ribonucleic acid; eGFR = estimated glomerular rate; OI/ADE = opportunistic infection/AIDs (autoimmune deficiency syndrome) defining event; IDU = intravenous venous use; ACEI/ARB = angiotensin converting enzyme inhibitor/angiotensin receptor blocker; highly active antiretroviral therapy (HAART).