The result for the ER negative tumour subgroup was similar to the whole group of tumours in that high TOX3 and LOC643714 mRNA levels were associated with positive lymph nodes (p < 0.001 and p = 0.01, respectively) and a positive PgR status, although only significant for TOX3 (p = 0.002, Additional file2: Table S3). Here, ESR1 is linked to neoplasm.