Death receptor signaling (3.87E-19), TNFR1 signaling (2.34E-13), induction of apoptosis by HIV1 (2.67E-12), apoptosis signaling (6.56E-12) and molecular mechanisms of cancer (2.13E-11) came out to be the top four most significant pathways (Figure 4C). Here, TNFRSF1A is linked to cancer.