Of these, ABC subfamily C member 1 (ABCC1), ABCC3, and ABCC4 are direct transcriptional targets of MYCN and expression levels of each of these genes are independent prognostic factors for neuroblastoma (Norris et al., 1996, 2005; Haber et al., 2006; Porro et al., 2010; Henderson et al., 2011). The gene discussed is ABCC4; the disease is neuroblastoma.