SULT1A1 and lung cancer: With regard to lung cancer, Pachouri et al. (2006) reported an increased risk of lung cancer associated with His/His (SULT1A1*2 isoform) genotype (OR = 1.40, 95% CI = 0.48–4.06), which was higher among smokers (OR = 3.9, 95% CI = 1.99–7.81).