In this study, T1DM-protective haplotypes were identified: DRB1*1401-DQB1*0503, DRB1*1303-DQB1*0301, DRB1*1502-DQB1*0601, DRB1*1301-DQB1*0603, DRB1*1101-DQB1*0301, DRB1*1301-DQB1*0603, DRB1*0701-DQB1*02. The gene discussed is HLA-DRB1; the disease is type 1 diabetes mellitus.