TGFB1 and chronic myelogenous leukemia, BCR-ABL1 positive: Imatinib, a small molecule inhibitor of c-Abl kinase used for the treatment of CML and gastrointestinal stromal tumors, blocked the stimulation of collagen synthesis, fibroblast proliferation and myofibroblast transdifferentiation elicited by TGF-β.