Yokoyama et al. indicated that mRNA level of PLSCR1 is a prognostic factor for acute myelogenous leukemia[32-34], and Huang et al. further demonstrated that PLSCR1 plays the antagonistic role regarding leukemia development and PLSCR1 induction increased cellular sensitivity to apoptosis[35]. The gene discussed is PLSCR1; the disease is acute myeloid leukemia.