TGM2 and type 1 diabetes mellitus: The two main aims of the present prospective cross-sectional study were to study the prevalence rate and clinical characteristics of CD in Saudi children with T1D using a combination of the most sensitive and specific screening serologic tests (Anti-TTG and EMA), and to determine the lower positive cut-off value of anti-TTG that best predicts histopathological diagnosis of CD in children with T1D.