This study reports on VDR expression at the mRNA level in spinal tissues of the idiopathic scoliosis patients with different age of deformity onset pointing at differences in VDRl isoform transcript abundance and indicating Tob2 and Med13 as genes differentially expressed in paravertebral muscles of the curve concavity of Juvenile and Adolescent Idiopathic Scoliosis. Here, MED13 is linked to idiopathic scoliosis.