In a current study from our lab on microRNA abnormalities in NZB/NZW F1 lupus model by using type I and type III interferons (IFN-α and IFN-λ) as exogenous disease accelerators, we identified upregulation of several microRNAs correlated to disease severity, yet not with the IFN treatment. Here, IFNA1 is linked to systemic lupus erythematosus.