CLU and age-related macular degeneration: Among the most common proteins identified in drusen from AMD donor eyes are: βB1-crystallin, Clusterin (APOJ), Complement Component 9 (CC9), αB-crystallin, βA3/βA4-crystallins, βB2-crystallin, βS-crystallin, Histone H2A2 (H2AE), Tissue inhibitor of metalloprotease 3 (TIMP3), Vitronectin, and Annexin 2 [11].