TNF and tuberculosis: The results founded by our group [106] demonstrated that individuals with or without a previous history of tuberculosis and exposed to M. tuberculosis showed a Th1 (TNF-α and IFN-γ) and Th2 (IL-10 and TGF-β) profile of cytokines, similar to that found by Demissie [105], with an IFN-γ production relatively low when compared to IL-10.