IGFBP2 and malaria: The FP2/3 homologs of the human malaria parasite P. vivax, known as vivapains (VX2-4), and the mouse malaria parasites Plamodium berghei (called bergheipain-2 or BP2) and Plasmodium vinckei (called vinckeipain-2 or VP2) have been characterized [13], [14], [46].