In order to investigate the pathophysiology of PINK1-associated PD in a large German family with a PINK1 nonsense mutation (c.1366C>T; p.Q456X), we performed combined phosphorous (31P) and proton (1H) magnetic resonance spectroscopic imaging (MRSI) on a 3-Tesla scanner in 11 family members who already had participated in a prior study with 18-Fluorodopa (FDOPA) positron emission tomography (PET) [10]. The gene discussed is PINK1; the disease is Parkinson disease.