From the downregulated genes of the EMT-core gene list, low FXYD3 expression showed a trend to poor overall survival of SCC patients (p = 0.17) and low expression of LAD1 (p = 0.00074), SLC7A5 (p = 0.0093) and SLPI (p = 0.043) significantly correlated with worse pCR of breast cancer patients. The gene discussed is SLC7A5; the disease is breast cancer.