In analyses adjusted for age, gender, APACHEIII score, presence of diabetes mellitus, end stage renal disease, chronic alcohol use, cirrhosis and smoking status, we identified a nominal association between the A allele of rs2069832 in IL6 by recessive modeling (ORadj 1.61; 95% confidence interval [CI], 1.04–2.48, P = 0.03) (Table 4). Here, IL6 is linked to stage 5 chronic kidney disease.