APC and adenoma: A bigger difference lies in the insertion/deletion ratio for these indels: while an approximately equal number of codons was disrupted by deletions and by insertions in both adenomas (47 versus 37) and adenocarcinomas (82 versus 89) for the other non-APC genes, significantly more codons were disrupted by deletions than by insertions for APC, 42 versus 18 for adenomas and 76 versus 19 for adenocarcinomas.