FTO and Alzheimer disease: While there were no differences in expression levels in tissue derived from the cerebellum or occipital lobe, microarray expression analyses of the amygdala tissue from the 19 AD and 10 control brains showed significantly lower expression of FTO in AD brains compared to control brains (mean gene expression intensity: 8.91±0.36 vs 9.57±0.23, p = 2.1E-5; Figure 3).