The purpose of our study was to assess the predictive value (VP) for AIG of the combined testing for anti-parietal-cell antibodies (PCA), anti-intrinsic-factor antibodies (IFA), anti-Helicobacter pylori (Hp) antibodies and gastrin, in patients suffering from iron-deficiency or vitamin B12 deficiency anemia, and to analyse the diagnostic efficacy of this laboratory profile in the selection of the subjects candidate to endoscopy. Here, GAST is linked to Iron deficiency anemia.