INSR and type 2 diabetes mellitus: A positive correlation between mean HOMA-IR and AI (P < 0.05, r = 0.71) and also between mean HbA1c and AI (P < 0.01, r = 0.86) suggests that improving blood glucose level and insulin receptor sensitivity may support to decline atherogenicity and cardiovascular complications in type 2 diabetes by using NO distillate.