We started with the analysis of the expression pattern of TS, RRM1 and RRM2 (two subunits of RR) in SK-Mel-19 and SK-Mel-29 cells 6 days post-infection with control or MYC shRNAs, i.e. at the time point when the majority of MYC-depleted cells underwent senescence [6]. The gene discussed is MYC; the disease is infection.