It has been shown that the level of the pro-inflammatory cytokines IL1β, IL6, IL8, and TNFα were positively correlated with the level of chronic gastritis but that correlation disappear in the presence of gastric atrophy and was inverse, for IL6 and IL8, in intestinal metaplasia (Isomoto et al., 2012). This evidence concerns the gene CXCL8 and chronic atrophic gastritis.