Of the lupus-associated NET proteins, the most in-depth work has involved LL37/cathelicidin, with the demonstration that this small cationic protein circulates in complex with chromatin fragments and anti-DNA autoantibodies in lupus serum, thereby enhancing stimulation of pDCs and protecting against DNase-mediated destruction (Lande et al., 2011). The gene discussed is CAMP; the disease is systemic lupus erythematosus.