Other proteins identified by immunofluorescence (no lupus-NET proteomics have been undertaken outside of the histone studies described below) include C1q (Leffler et al., 2012), NE (Garcia-Romo et al., 2011; Villanueva et al., 2011), histones (Villanueva et al., 2011; Liu et al., 2012), HMGB1 (Garcia-Romo et al., 2011), HNP (Lande et al., 2011), IL-17 (Villanueva et al., 2011), LL37/cathelicidin (Lande et al., 2011; Villanueva et al., 2011), and MPO (Garcia-Romo et al., 2011; Lande et al., 2011; Villanueva et al., 2011). The gene discussed is KLK8; the disease is systemic lupus erythematosus.