CD40LG and atherosclerosis: A wealth of active and passive immunization studies in mice and the identification of atheroprotective IgM antibodies, implicated B cells in attenuating atherosclerosis (Palinski et al., 1995; Ameli et al., 1996; Freigang et al., 1998; Nicoletti et al., 1998; Zhou et al., 2001; Binder et al., 2003, 2004; Faria-Neto et al., 2006).