TPMT and neuropathy: We found statistically significant associations of four SNP markers (rs4646316, rs4380755, rs5008499, and rs6591256) in or near COMT, TPMT, and GSTP1 with neuropathy and five SNP markers (rs3788306, rs12189790, rs17420046, rs6938294, and rs6912842) with ototoxicity at the nominal p-value of 0.05.