GSTP1 and peripheral neuropathy: Variants in glutathione S-transferase pi (GSTP1), which encodes an enzyme that detoxifies chemotherapeutic agents by conjugating reactive electrophiles to glutathione (Mannervik et al., 1985), appear to be important in the development of long-term peripheral neuropathy and ototoxicity in adult TGCT patients (Oldenburg et al., 2007a,b).