A recent study has shown that the NF-κB-regulated microRNAs miR-9, miR-125b, miR-146a, and miR-155 are upregulated in both AMD and Alzheimer's disease and that miR-146a and miR-155 target the 3′-UTR of CFH, thereby downregulating CFH[76]. The gene discussed is CFH; the disease is early-onset autosomal dominant Alzheimer disease.