Examination of Stat3 levels in certain NSCLC lines demonstrated that Src is a major Stat3 activator, transducing signals from EGFR and IL6 that lead to apoptosis inhibition[12], while in another report[13] Src inhibition in different NSCLC lines was found to actually increase Stat3-ptyr705. This evidence concerns the gene EGFR and non-small cell lung carcinoma.