The correlation analysis indicated that there was a significantly positive correlation between Hlx and T-bet, and a negative correlation between Hlx and GATA3. Our data also showed that the expression rates of Runx3 in patients with gastric cancer (especially poorly differentiated adenocarcinoma) were obviously lower than that in control groups and there was a positive correlation between the expression of Runx3 and T-bet or IFN-γ in patient. The gene discussed is RUNX3; the disease is adenocarcinoma.