C1R and neoplasm: More importantly, although iNKT cells were strongly activated by αGC-pulsed APCs, such as C1R-CD1d or moDCs, as seen by CD107a expression and cytokine release, they rather killed the APCs and to a lesser extent the tumor cells, indicating that bystander killing by iNKT cells was inferior to the CD1d-mediated cytotoxicity.