STAT1 and flatulence: Given recent results that indicate that chromatin remodeling factors such as Brahma-related gene (BRG)-1 are differentially recruited to GAS sites after Toxoplasma infection to inhibit STAT1-mediated transcription [14], and that Toxoplasma infection can modulate chromatin modifications resulting in changes in gene expression [36], a transient plasmid reporter that is not integrated into the genome and does not have a normal chromatin structure also may not be an accurate measure of STAT1 transcriptional activity [37], [38].