G6PD and Plasmodium falciparum malaria: The main limitation to the use of primaquine, either for the radical cure of Plasmodium vivax or Plasmodium ovale malaria, or as a gametocytocide in Plasmodium falciparum malaria, is the risk of haemolysis in patients who are glucose 6-phosphate dehydrogenase (G6PD) deficient[1,2].