These dose–response observations in subjects with the African A- G6PD variant together with experience in large numbers of soldiers (see below) led to recommendation of a modified radical curative regimen in P. vivax and P. ovale malaria of 0.75 mg base/kg once weekly for eight weeks in patients with the A- type of G6PD deficiency[4,35]. This evidence concerns the gene G6PD and malaria.