CALCA and infection: Rather, RTD-1 administration appeared to protect infected animals by reducing pulmonary inflammation and suppressing IL-1α, IL-1β, IL-6, IL-12, CXCL1 (KC), CCL2 (MCP-1), CCL3 (MIP-1α), and CCL5 (RANTES) 2–4 days post-infection [14].