Table 5 lists three separate associations between rs17172430 and HD at 9p21 (i.e. the CDKN2A/B locus); these should not be considered independent. The separate listings reflect both that two different approaches were used to analyze the data, and the fact that the global approach often picked up adjacent regions that were separated due to frequency drops caused by genomic breakpoints in just a few patients (Table S1). Figure 4 provides a clear illustration of the association between rs1015793 (used as a surrogate for rs17172430 in UMU data) and HD at 9p21 locus. The gene discussed is CDKN2A; the disease is Huntington disease.