ART4 and Ebola hemorrhagic fever: To this end we constructed rAd26 and rAd35 vectors expressing the glycoproteins of five selected filovirus strains (Ebola Zaire, Ebola Sudan/Gulu, Ebola Ivory Coast, Marburg Angola, or Marburg Ravn) and evaluated these vectors for their ability to induce strain specific and cross-reactive cellular and humoral immune responses in a mouse model.